Become an Entradan

Jump to Open Positions

We exist to help patients and their families live better lives.

Our Values

We love science and our values bind us together to create an environment that is as unique as our research. We are building a company culture where everyone can belong, contribute and grow. Join us.

We connect to and are inspired by our mission to drive innovation and unlock our full potential. We strive for this every day and in every role, so that each Entradan can grow and fully contribute to our community.

Entrada takes care of you so you can focus on our science and mission; our perks and benefits are designed to meet your needs regardless of what season of life you are in. We celebrate the big and the small and rally around our collective ability to make a difference in the lives of patients and their families.

Humanity

We genuinely care about patients and about one another.
Tenacity

We're relentless and persistent in the pursuit of developing therapies for patients.
Creativity

We're creative problem solvers.
Collaboration

We're more than the sum of our parts.
Curiosity

We've got a growth mindset.

Listen as Dipal Doshi, our CEO, shares more about our mission, the culture we’re building and how we’re working together to develop new therapies to treat devastating diseases.

Meet Our Entradans

BK Choi, PhD

Senior Principal Scientist, Product Development
Murali Mallem

VP and Head of CMC
Kimberli Kamer, PhD

Senior Scientist II, Pharmacology
Nanjun Liu

Director, Bioanalytical Lead
Nick Long, PhD

Senior Scientist II, Antibody and Protein Engineering
Sara Blake

Senior Research Associate, Neuromuscular and Cardiac Biology
Nelsa Estrella, PhD

Director, Neuromuscular Therapeutics
Leo Qian, PhD

Co-founder & VP, Discovery Research

Placeholder for video showing work life at Entrada

What Sets Us Apart:

Since our inception, we have worked to build a high-performing, inclusive and diverse team, which is a core element of our culture. Entradans are committed to making a difference in the lives of patients, their families and care partners. We believe that by embracing differences, we have a unique advantage in challenging the status quo to apply innovative thinking to long-existing medical challenges.

56% Identify as women
52% Asian, Hispanic, Latino, Black, or African American
62% Of our Senior Leadership Team and Board is made up of women and minorities

Self-reported, as of March 2024.

Our Comprehensive Benefits:

Wellness

We offer a $500 wellness benefit to support you and your individual priorities.
Fuel

Subsidized lunches, snacks, cold brew, drinks and treats.
Commuter Benefits

We offer $300 to cover your commute, however you do it.
Connections

Organized coffee dates, company-wide activities and gatherings.
Development & Learning

We offer individual and broad approaches to growth.
Mobile Stipend

We help you stay connected by offsetting your data plan.
Swag

We always offer opportunities to show your love for Entrada.
Parental Leave

We give you time to connect and bond with your new child.
Milestones

Personal or professional, we celebrate the big and small stuff.

Excited by what you see? Check out our Current Openings and Benefits and apply to join the Entrada team!

Learn About Our Benefits

We wish we didn’t have to say this, but please beware of fraud

Some individuals may receive fraudulent interview requests or employment offers from a person or organization posing as Entrada Therapeutics. They will often request personal information and/or payment to complete the interview or hiring process. Recent scams have utilized slightly modified versions of this domain or have used public domains (gmail, yahoo, outlook, etc) for their fraudulent communications. If you fear that you have been a victim of an employment application scam, please contact the Internet Crimes Complaint Center at www.IC3.gov.

Such as passport details or social security numbers, financial information or payment from job seekers. During our formal recruitment process, you will interview with a member of the recruitment team and any email communications received from an employee will end in “entradatx.com”. In addition, all legitimate openings and positions will be posted to our website at https://www.entradatx.com/careers.

Current Openings

Check out our current openings below.

Senior Scientist I, Analytical Development & CMC

Boston, MA

Learn More
Senior Director, Clinical Pharmacology

Boston, MA

Learn More
Associate Director, Clinical Supply Chain

Boston, MA

Learn More
Director, Biostatistics

Boston, MA

Learn More
Senior Scientist I, Bioanalytical

Boston, MA

Learn More
Senior Research Associate, Formulation and Analytical Chemistry (CONTRACT)

Boston, MA

Learn More
Research Associate, Antisense Oligonucleotide (CONTRACT)

Boston, MA

Learn More

There's more to explore

Boston, MA

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You are patient focused and excited about the opportunity to bring your expertise in analytical method development to our team. You enjoy a fast-paced environment and juggling competing priorities. You work best not siloed, but as a collaborator across different functional groups, including Discovery, Process Development, Pharmacology, Product Development, and CRO/CDMOs. You bring strong interpersonal skills to effectively build working relationships inside and outside the company.

The Opportunity

We are seeking a Senior Scientist who is experienced, highly energetic, and committed to developing new and improving existing analytical methods. This role will be responsible for the analytical and quality control aspects related to safety, identity, and purity analysis of oligonucleotides, biologics and biologics conjugates. This work will support early and late-stage CMC activities for drug substances and drug products used in the non-clinical and clinical studies.

Responsibilities

Develop and lead analytical method transfer, optimization, and qualification activities for the release, stability and extended characterization of different therapeutic modalities, including oligonucleotides, therapeutic enzymes, proteins, and protein conjugates.
Partner with CDMOs on analytical method transfer, phase-appropriate qualification, reference standard generation and qualification, stability program management and other quality control related activities.
Prepare and review standard test methods, reports, protocols, regulatory filings (IND, IMPD, etc.), patent applications, and publications (including review for technical correctness and regulatory compliance).
Serve as a subject matter expert on multiple projects, and authors and reviews change control documents, deviations, and investigation reports.
Give technical guidance and training to other laboratory staff as required.
Mentor and potentially manage junior level scientists and research associates.
Communicate, work closely and provide analytical updates to cross-functional team members. Maintain proficiency in the latest analytical technologies as well as emerging analytical development strategies.
Review and evaluate new methodologies /techniques to add to laboratory capabilities.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

A Ph. D in Biochemistry, Analytical Chemistry or a related discipline with a minimum of 4 years or MS and 8+ years of relevant biologics analytical method development in a Biotech or Pharmaceutical industry under GMP environment.
A strong background and in-depth working knowledge of separation sciences, including but not limited to: HPLC (RP, HIC, HILIC, IEX and SEC) and CE (CE-SDS, cIEF). LC-MS and LC-MS/MS experience is a plus.
Quality control experience for the GMP manufacturing is highly valued, including but not limited to analytical method transfer, phase-appropriate method qualification/validation, DS and DP specification setting, in-process/release/stability testing, and batch disposition.
Excellent communication (written and verbal) and interpersonal skills.
Strong attention to detail and results driven in line with project and team objectives.
Ability to handle multiple high priority tasks in parallel to meet organizational goals.

The Perks

By becoming a team member here at Entrada, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

Privacy Statement

Entrada Therapeutics, Inc. (the “Entrada,” “we,” “us,” or “our”) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.

Apply

Boston, MA

The Organization

The Perfect Addition to Our Team

You are excited about the opportunity to develop and build the Clinical Pharmacology function at Entrada. You enjoy a fast-paced environment and juggling competing priorities. You follow up and follow through, efficiently connecting problems with solutions. You work successfully in a team environment, with strong people skills to effectively build working relationships inside and outside of the company.

The Opportunity

Reporting into the VP, Clinical Development, the ideal candidate will have a strong knowledge of best practices in Clinical Pharmacology and Pharmacometrics, extensive experience in designing and executing clinical pharmacology studies, and a demonstrated ability to make data-driven decisions based on preclinical and clinical information.

Responsibilities

Responsible for strategic planning and execution of clinical pharmacology and modeling and simulation (M&S) activities as a core member of program teams, and leading collaborations with cross-functional teams as well as external partners as necessary.
Drives the necessary PKPD, exposure response and translational modeling and quantitative pharmacology activities to achieve mechanistic understanding of novel drug candidates, and support optimal dose and dosing schedule decisions.
Supervises, plans, designs, executes and reports program-specific clinical pharmacology studies (e.g. assessment of QT, ADME, DDI strategy, special populations, etc.) to support development and registration of Entrada products, by working cross-functionally with preclinical development team, clinical development, biomarkers, and other partners.
Partners with research leads for the design and data analysis/interpretation of pharmacokinetic (PK), toxicokinetic and pharmacodynamics (PD) aspects of preclinical studies.
Works in close collaboration with colleagues in discovery, nonclinical research, clinical development, clinical operations, and project management to author/contribute to IND/CTA submissions and other regulatory submissions, initiation of clinical development programs, late-stage development, and interactions with health authorities.
Monitors work with CROs and other external vendors to ensure compliance with agreed protocols, quality standards and timelines.
Accountable for adherence to agreed timelines and budgets to ensure execution of deliverables from Clinical Pharmacology studies and programs Collaborate cross functionally with all relevant areas to support corporate objectives.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

Ph.D. in pharmaceutics, pharmacokinetics, pharmacology, pharmacometrics, or related discipline, or Pharm.D. or M.D. with relevant experience.
Minimum 8 years of experience in the biotechnology or pharmaceutical industry including a strong understanding of early and late drug development process from IND/CTA through NDA/BLA.
Direct experience in leading clinical pharmacology activities in drug development programs, from early exploratory studies to Phase 2/3 programs.
Experience in translational research and/or pharmacometrics and its application to drug development, including PKPD, exposure response and translational modeling activities to support optimal dose and dosing schedule decisions.
Strong fundamental or research background with interest in understanding PK and PK/PD data in the context of complex biology.
Preferred scientific and clinical background in Neuromuscular and/or Neurology.
Preferred experience with oligonucleotides.
Proficient in using Phoenix WinNonlin, R, NONMEM, MATLAB or other pharmacokinetic and modeling software.
Strong documentation and organizational skills, as well as proven ability to be self-motivated and able to work independently.
Excellent communication and presentation skills to efficiently relay information to project teams and other key stakeholders.
Understand cross-functional needs and ability to serve as a matrix leader or lead in a matrix environment.
Ability to effectively recruit, guide, and train junior staff. #LI-Remote

The Perks

Third Party Staffing Agencies

Privacy Statement

Apply

Boston, MA

The Organization

The Perfect Addition to Our Team

You are patient focused and excited about the opportunity to lead, establish, and execute the clinical supply functionality at Entrada. You enjoy a fast-paced environment and juggling competing priorities. You follow up and follow through, connecting problems with solutions efficiently. You work successfully in a team environment with strong interpersonal skills to effectively build working relationships inside and outside the company.

The Opportunity

We are seeking a Clinical Supply Chain leader who is experienced, highly energetic, and committed to helping develop and execute Entrada’s supply strategy across all clinical programs. The individual’s day-to-day will span across demand management, supply planning, and vendor forecast management, working cross-functionally internally and with external vendors to ensure delivery of an effective supply chain strategy.

Responsibilities

Mange Entrada’s end-to-end supply chain, including demand/supply/capacity planning, material sourcing, label text generation/approval (MELT), clinical labeling and re-labeling of vials (expiration date updates), packaging, inventory management, cold chain shipping, import and export, and global distribution.
Work with cross-functional team to develop study-specific IRT specifications and requirements from an Investigational Product (IP) management perspective.
Identify supply accountability tracking and ensure Master, Pharmacy, Subject Logs are appropriate.
Ensure appropriate documentation of IP supply activities is provided to the Trial Master File.
Develop and follow appropriate Supply Chain SOPs.
Build and execute forecast models for ongoing and future clinical studies.
Manage sourcing of ancillary supplies for IV infusion for clinical sites
Support pharmacy manual and dose preparation generation.
Work closely with CMC, Clinical Operations and clinical packaging sites to ensure clinical drug inventory levels are maintained in accordance with study plans.
Identify and oversee third-party vendors to support Entrada’s global clinical programs.
Develop appropriate supply risk mitigation strategies and identify and communicate risks to clinical program timelines from manufacturing delays.
Ensure adherence to applicable regulations, including FDA, EMA, ICH, GCP, GMP.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

Bachelor’s degree in supply chain, scientific or related field required with 8+ years of Clinical Supply Chain management in the pharmaceutical or biotechnology industry.
Extensive Knowledge and proficiency of IRT system use and development for open label and double-blind studies
Strong working knowledge of GMP, GCP regulations, labeling, packaging and distribution operations.
Experience working with third-party P&L CMOs and managing supply chain vendors.
Strong organizational and forecasting skills.
Ability to strategically plan, proactively organize and manage multiple projects simultaneously.
Experience managing temperature-controlled cold chain shipments globally.
Proficiency in Microsoft applications and Inventory Management systems.
Excellent communication (verbal and written) and interpersonal skills.
Ability to exercise independent judgment with minimal supervision.
This is a US based remote position, with preference given to local New England based candidates. This role will require minimum quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA.

The Perks

Third Party Staffing Agencies

Privacy Statement

Apply

Boston, MA

The Organization

The Perfect Addition to Our Team

You are excited about the opportunity to lead biostatistics and support the progress of our clinical trials here at Entrada. You are well organized and will be able to independently provide strategic statistical input to drug development planning. You enjoy a fast-paced environment and juggling competing priorities and are willing to jump in and help wherever it is needed. You drive for results, efficiently connecting problems with solutions. You work successfully in a team environment and have strong interpersonal skills, to effectively build working relationships inside and outside of the company.

The Opportunity

Reporting to the SVP, this individual will guide day-to-day statistical operations and the development of statistical methodologies. You will work with internal and external stakeholders to support and oversee a portfolio of clinical studies. The individual will support the strategic growth of the biostatistics function at Entrada.

Responsibilities

Responsible for leading statistical strategy for assigned drug programs, including input to clinical development plans, clinical study concepts and protocols design, SAPs, clinical study reports, regulatory documentation and associated publications
Accountable for oversight of the production of biostatistics deliverables (TFLs, including planned, post-hoc, and/or exploratory analyses) as performed by internal and/or external resources
Serve as a key leader in the clinical product team, providing statistical strategy and inputs in protocols, data monitoring committee (DMC) charters, clinical study reports (CSR) and other study-level documents
Serve as the biostatistical lead to support the team to design and support data collection, analyses, interpretation of efficacy, safety, and biomarker results
Author/review the statistical analysis plan for clinical trials and for integrated summaries of safety/effectiveness (ISS/ISE), and authors or oversees the development of shells for tables, figures and listings
Define/review the randomization procedures and oversight of the production of randomization lists
Review study Case Report Forms, data management plan and other data management related documentation to ensure that specific statistical requirements defined in the study protocol are met
Oversee outsourced statistical CRO activities and deliverables, ensuring high quality and timely delivery
Support and participate in the development of department strategies and cross functional initiatives on standards, infrastructure and processes

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

PhD with 10 + years or MS and 12 + years of relevant statistical analysis roles in the biotech/pharmaceutical industry is required
Experience with a broad array of statistical approaches and experience in proposing novel approaches to support acceleration of clinical programs in rare disease trials
Demonstrated track record in various disease indications, endpoints and appropriate statistical/regulatory requirements
Experience in supporting responses and submissions to health authorities (FDA, EMA)
Strong vendor management and oversight experience
Proficiency in statistical analysis software (SAS and R) and sample size calculation software (e.g. EAST and/or NQuery)
Excellent verbal and written communication skills
This is a US based remote position, with preference given to local New England based candidates. This role will require minimum quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA.

Preferred Skills:

Direct line people management
Deep understanding of Biomarkers, PK/PD, PRO and RWE
Neuromuscular drug development experience #LI-Remote LI-JF1

The Perks

Third Party Staffing Agencies

Privacy Statement

Apply

Boston, MA

The Organization

The Perfect Addition to Our Team

As a member of the Bioanalytical group in the Product Development team, you are versatile, self-motivated, timeline- and process-oriented, and looking forward to rolling up your sleeves and diving into details and overcoming obstacles. You will successfully lead and coordinate bioanalytical support functions across various modalities, including oligonucleotides and biologics, to perform both qualitative and quantitative bioanalysis in complex biological matrices. You will lead as a technical expert to provide timely bioanalytical support for discovery projects and pre-IND clinical candidate studies. Additionally, you will be a key contributor to documents supporting regulatory filings and will have the opportunity to contribute to scientific publications.

You also enjoy a fast-paced environment and juggling competing priorities. You have excellent verbal and written communication skills, you follow up and follow through, bringing solutions to problems efficiently. You work successfully in a team environment with strong interpersonal skills to effectively build working relationships inside and outside the company.

The Opportunity

Work within the Bioanalytical group to enable the full spectrum of EEV-conjugated modalities development from early discovery candidate selection through late-stage process development.

Responsibilities

Develop, qualify, and implement bioanalytical assays using LC-MS/MS to support PK and biodistribution studies for therapeutic candidates including oligonucleotides, biologics, and peptides.
Perform both qualitative and quantitative bioanalysis in various biological matrices (e.g. plasma, CSF, urine, and tissues, etc.) across different species. Generate high-quality data and reports in a timely manner to meet project deliverables.
Lead or support bioanalytical deliverables for discovery project activities, candidate enabling studies, and clinical candidate IND enabling studies; provide scientific guidance and technical support on method development, qualification, and sample analysis in-house as well as at CROs.
Mentor team members and colleagues on scientific concepts and best practices on technical details regarding various bioanalytical approaches.
Lead troubleshooting efforts for bioanalytical assays; proactively identify and solve technical challenges/bottlenecks to maintain/improve assay robustness and efficiency.
Implement processes to ensure timelines are met with data integrity; communicate and interface with stakeholders including discovery, preclinical, CMC, and external CROs to define and deliver strategies in a flexible manner to support project timelines across multiple programs.
Interpret and present bioanalytical data internally as well as in cross-functional team meetings; serve as an SME on behalf of the bioanalytical team for technical, strategic, and prioritization discussions to advance program objectives.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

A PhD in chemistry, biochemistry, pharmacology, analytical chemistry, or a related field with at least 4 years of bioanalytical science experience, or an equivalent combination of education and experience (e.g. MS degree with at least 7 years of experience) will be considered.
Proven track record of fostering a collaborative work environment.
Subject matter expert with extensive hands-on experience with developing, qualifying, implementing, and troubleshooting LC-MS/MS to support a variety of therapeutic modalities; direct work with oligonucleotides and/or biologics strongly preferred.
Ability to work independently in a fast-paced, competing priority environment, as well as in a cross-collaborative team setting
Excellent communication skills (oral and written) and a successful track record of cross-disciplinary collaboration are essential.
Knowledge/experience of pharmacokinetics, drug metabolism, immunogenicity, and biomarker studies are highly desirable.
Knowledge and experience with assay development, transfer, qualification, and validation to external CROs in a GLP/GxP environment is considered a plus.

The Perks

Third Party Staffing Agencies

Privacy Statement

Apply

Boston, MA

The Organization

The Perfect Addition to Our Team

You are a highly motivated Senior Research Associate who thrives in a collaborative and fast-paced environment. You are detail-oriented and interested in working at the intersection of our Formulation and Analytical Development teams.

The Opportunity

In this role, the Senior Research Associate will be responsible for the formulation of drug substances and the operation of multiple instruments including HPLC, LC-MS, and UV-Vis. They will formulate and characterize the formulation of oligonucleotides, peptides, conjugates, and other novel molecules. The ideal candidate will also manage the chemical inventory, ordering chemicals and supplies, and maintaining a good experimental record will be a key part of your role. The Senior Research Associate will interpret and present research data and findings in internal scientific meetings as well as prepare procedures and technical reports.

Responsibilities

• Lead oligonucleotide/peptide/conjugates formulation for in vitro and in vivo studies to support all discovery projects.
• Analyze formulation samples using various instruments such as LCMS and HPLC.
• Coordinate with neuromuscular and discovery biology teams for data and sample transfers.
• Organize and document all experimental data and connect with all related in vitro and in vivo.
• Contribute to reports and presentations. During internal and external meetings, you should be ready to interpret and present research data and findings.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

BS (4+ years relevant experience) or MS degree (2+ years relevant experience) in Pharmaceutical Sciences, Chemistry, Biology, Bioengineering, or a related field.
Hands-on experience of oligonucleotide/peptide/conjugates formulation for in vitro and in vivo biological assays is required.
Ability to execute pipetting tasks accurately and efficiently to maintain the integrity of experimental results.
Hands-on experience with analytical instrumentation such as UV-Vis, IEX-HPLC, RP-HPLC, LCMS for formulation characterization is required.
An understanding of laboratory safety and best practice is required.
Experience with aseptic handling techniques is preferred.
Attention to detail and the ability to thoroughly document experimental work in electronic lab notebooks (ELNs).
Understanding of oligonucleotide/peptide chemistry as well as the knowledge of analytical chemistry is a plus.
Excellent written skills to author SOPs and technical reports, and verbal communication skills to present internally and externally.
To be effective on our team, you must have the ability to interact effectively in a multi-disciplinary, fast-paced research environment as well as the ability to multi‐task to meet research and development goals.

The Perks

Third Party Staffing Agencies

Privacy Statement

Apply

Boston, MA

The Organization

The Perfect Addition to Our Team

You should be versatile, self-motivated, and looking forward to rolling up your sleeves, as you’ll be involved in all aspects of oligonucleotides. You will be supporting efforts for antisense oligonucleotides, small interfering ribonucleic acids and gene editing platforms. You should be ready to support our team of drug discovery scientists as we design, prepare and characterize oligonucleotide constructs and carry out analytical assays for functional validation both in vitro and in vivo.

The Opportunity

In this role, the Research Associate will have the opportunity to be involved in a lot of different aspects of our oligonucleotide work; for example, processing and analyzing samples from in vitro and in vivo studies will be one of your areas of work. They will be expected to work through techniques like RNA/protein extraction, RT-PCR, RT-qPCR, ELISA, and Western Blot. You’ll also have the opportunity to maintain and culture cell lines for in vitro studies, as well as developing and executing cell-based assays for validating biological activity of oligonucleotide therapeutics. Lastly, the Research Associate will have the opportunity to prepare SOPs and other reports and publications.

Responsibilities

• Maintain and culture primary and secondary cell lines for in vitro studies.
• Develop and execute cell-based assays for validating biological activity of oligonucleotide therapeutics.
• Use techniques like RNA/protein extraction, RT-PCR, RT-qPCR, ELISA, and Western Blot to process and analyze samples from in vitro and in vivo studies.
• Produce high quality data that will contribute to new therapeutic development.
• Contribute to reports and presentations. During internal and external meetings, you should be ready to interpret and present research data and findings.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

BS/MS in molecular biology, pharmacology, biochemistry or similar field. At least 2+ years’ experience in a lab or industry experience.
Hands-on biochemistry experience with techniques like RT-PCR, qPCR, ELISA, fluorescence microscopy, cell culture and western blotting and other protein assays.
Hands-on experience with oligonucleotides is a plus.
To be effective on our team, we need you to bring excellent working knowledge and familiarity with graphic software and Microsoft Office.
You should be collaborative and a strong communicator and can multi-task effectively.

The Perks

Third Party Staffing Agencies

Privacy Statement

Apply

Become an Entradan

Our Values

Meet Our Entradans

What Sets Us Apart:

Our Comprehensive Benefits:

We wish we didn’t have to say this, but please beware of fraud

Please be aware of fraudulent hiring outreach and job offers

Please note that Entrada Therapeutics will not request any personal information

Current Openings

There's more to explore

Who We Are

Platform

Pipeline

Senior Scientist I, Analytical Development & CMC

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement

Senior Director, Clinical Pharmacology

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement

Associate Director, Clinical Supply Chain

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement

Director, Biostatistics

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement

Senior Scientist I, Bioanalytical

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement

Senior Research Associate, Formulation and Analytical Chemistry (CONTRACT)

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement

Research Associate, Antisense Oligonucleotide (CONTRACT)

The Organization

The Perfect Addition to Our Team

The Opportunity

Responsibilities

The Necessities

The Perks

Third Party Staffing Agencies

Privacy Statement