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We exist to help patients and their families live better lives.

Our Values

We love science and our values bind us together to create an environment that is as unique as our research. We are building a company culture where everyone can belong, contribute and grow. Join us.

We connect to and are inspired by our mission to drive innovation and unlock our full potential. We strive for this every day and in every role, so that each Entradan can grow and fully contribute to our community.

Entrada takes care of you so you can focus on our science and mission; our perks and benefits are designed to meet your needs regardless of what season of life you are in. We celebrate the big and the small and rally around our collective ability to make a difference in the lives of patients and their families.

  • Humanity

    We genuinely care about patients and about one another.

  • Tenacity

    We're relentless and persistent in the pursuit of developing therapies for patients.

  • Creativity

    We're creative problem solvers.

  • Collaboration

    We're more than the sum of our parts.

  • Curiosity

    We've got a growth mindset.

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Listen as Dipal Doshi, our CEO, shares more about our mission, the culture we’re building and how we’re working together to develop new therapies to treat devastating diseases.

Meet Our Entradans

  • BK Choi, PhD, Senior Principal Scientist, Product Development
    BK Choi, PhD
    Senior Principal Scientist, Product Development
  • Murali Mallem, VP and Head of CMC
    Murali Mallem
    VP and Head of CMC
  • Kimberli Kamer, PhD, Senior Scientist, Pharmacology
    Kimberli Kamer, PhD
    Senior Scientist II, Pharmacology
  • Nanjun Liu, Associate Director, Bioanalytical Lead
    Nanjun Liu
    Director, Bioanalytical Lead
  • Nick Long, PhD, Senior Scientist, Antibody and Protein Engineering
    Nick Long, PhD
    Senior Scientist II, Antibody and Protein Engineering
  • Sara Blake, Research Associate II, Neuromuscular and Cardiac Biology
    Sara Blake
    Senior Research Associate, Neuromuscular and Cardiac Biology
  • Nelsa Estrella, PhD, Associate Director, Neuromuscular Therapeutics
    Nelsa Estrella, PhD
    Director, Neuromuscular Therapeutics
  • Leo Qian, PhD, Co-founder & VP, Discovery Research
    Leo Qian, PhD
    Co-founder & VP, Discovery Research
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What Sets Us Apart:

Since our inception, we have worked to build a high-performing, inclusive and diverse team, which is a core element of our culture. Entradans are committed to making a difference in the lives of patients, their families and care partners. We believe that by embracing differences, we have a unique advantage in challenging the status quo to apply innovative thinking to long-existing medical challenges. 

  • 56% Identify as women
  • 52% Asian, Hispanic, Latino, Black, or African American
  • 62% Of our Senior Leadership Team and Board is made up of women and minorities

Self-reported, as of March 2024.

Our Comprehensive Benefits:

  • Wellness

    We offer a $500 wellness benefit to support you and your individual priorities.

  • Fuel

    Subsidized lunches, snacks, cold brew, drinks and treats.

  • Commuter Benefits

    We offer $300 to cover your commute, however you do it.

  • Connections

    Organized coffee dates, company-wide activities and gatherings.

  • Development & Learning

    We offer individual and broad approaches to growth.

  • Mobile Stipend

    We help you stay connected by offsetting your data plan.

  • Swag

    We always offer opportunities to show your love for Entrada.

  • Parental Leave

    We give you time to connect and bond with your new child.

  • Milestones

    Personal or professional, we celebrate the big and small stuff.

Excited by what you see? Check out our Current Openings and Benefits and apply to join the Entrada team!

Learn About Our Benefits

We wish we didn’t have to say this, but please beware of fraud

Some individuals may receive fraudulent interview requests or employment offers from a person or organization posing as Entrada Therapeutics. They will often request personal information and/or payment to complete the interview or hiring process. Recent scams have utilized slightly modified versions of this domain or have used public domains (gmail, yahoo, outlook, etc) for their fraudulent communications. If you fear that you have been a victim of an employment application scam, please contact the Internet Crimes Complaint Center at www.IC3.gov. 

Such as passport details or social security numbers, financial information or payment from job seekers. During our formal recruitment process, you will interview with a member of the recruitment team and any email communications received from an employee will end in “entradatx.com”. In addition, all legitimate openings and positions will be posted to our website at https://www.entradatx.com/careers.

2023 Best Places to Work Presented by Biospace - see our open positions Boston Globe Best Places to Work in Massachusetts 2024 - see our open positions Winner MassEcon Impact Award - see our open positions

Current Openings

Check out our current openings below.

There's more to explore

Who We Are

Meet our leadership team

Platform

Learn about our EEV™ Platform

Pipeline

Discover our pipeline of programs

Principal Scientist, DMPK

Boston, MA

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You are a highly motivated, collaborative, and innovative Drug Metabolism and Pharmacokinetics expert with experience driving preclinical DMPK activities. We have a diverse pipeline and as such you should have experience across both small and large molecules and have hands on experience leading the design, analysis, and interpretation of preclinical in vitro and in vivo studies. You are an exceptional communicator and a natural collaborator who is excited about the opportunity to contribute to this function and work closely with cross functional leaders.

The Opportunity

The ideal candidate will serve as a subject matter expert working within the DMPK team to drive the DMPK strategy across all designated programs and pipelines. They will have the opportunity to design, manage, and execute DMPK deliverables, and will be responsible for analyzing, interpreting, and authoring/reviewing ADME and PK/PD reports.

Responsibilities

  • Lead all PK- and ADME-related efforts for designated program(s).
  • Communicate and present relevant information across all areas of the organization, regardless of level.
  • Select and manage PK/TK, PK/PD, and ADME CROs.
  • Author and review PK/TK, PK/PD, and ADME reports.
  • Author and review relevant PK/TK, PK/PD, and ADME sections of regulatory submission documents (e.g. investigational new drug (IND), investigator brochure (IB), clinical trial application (CTA), etc)
  • Review associated reports, including clinical, toxicology, pharmacology, and bioanalysis.
  • Collaborate with clinical teams, including pharmacology, biomarkers, development, and operations.
  • Collaborate with non-clinical development teams, including toxicology and bioanalysis.
  • Collaborate with discovery teams to guide future programs and better understand mechanisms of action.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • PhD in pharmacology or similar field with 8+ years of DMPK experience in an industry setting or a MS with 12+ years of relevant experience.
  • Expertise with ADME studies and assays, with a proven track record of strategizing and troubleshooting based upon raw data.
  • Vendor Management experience, specifically managing CROs.
  • Additional experience with other aspects of ADME, bioanalytical techniques, PK/PD, toxicokinetics, pre-clinical PK/PD modeling, and translational biology are strongly preferred.
  • Experience with oligonucleotide-based modalities.
  • Experience authoring and reviewing DMPK-related reports and regulatory documents for health authority submissions is highly desirable.
  • You should be naturally collaborative and a strong communicator, and let’s not forget the ability to multi-task effectively and work within aggressive timelines– these are key to being successful in Entrada’s fast paced environment.
  • This is a US based remote position, with preference given to local New England based candidates. This role will require minimum quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA. #LI-Remote #LI-CZ1

The Perks

By becoming a team member here at Entrada, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

Privacy Statement

Entrada Therapeutics, Inc. (the “Entrada,” “we,” “us,” or “our”) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.

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